WebAcute non-lymphocytic leukemia in adults and children. Cytarabine is also approved to prevent and treat: Meningeal leukemia ( leukemia that has spread to the meninges ). It is given as intrathecal therapy. Cytarabine may also be used to treat: Acute lymphoblastic leukemia (ALL). Chronic myelogenous leukemia (CML) in blastic phase. CYTARABINE (sye-tare'a-been) ARA-C, Cytosar-U, Cytosine Arabinoside, DepoCyt, Tarabine Classifications:antineoplastic; antimetabolite, purine antagonist; immunosuppressant Prototype: 6-mercaptopurine Pregnancy Category: D Availability 10 mg/mL liposomal, 20 mg/mL, 100 mg, 500 mg, 1g, 2 g injection … See more Pyrimidine analog with cell phase specificity affecting rapidly dividing cells in S phase (DNA synthesis). In certain conditions prevents development of cell from G1to S phase. Interferes with DNA and RNA synthesis. See more To induce and maintain remission in acute myelocytic leukemia, acute lymphocytic leukemia, and meningeal leukemia and for treatment of lymphomas. Used in combination with other antineoplastics in established … See more Antineoplastic agent which has strong myelosuppressant activity. Immunosuppressant properties are exhibited by obliterated cell-mediated immune responses, such as delayed hypersensitivity skin … See more History of drug-induced myelosuppression; immunization procedures; pregnancy (category D) particularly during first trimester, lactation. … See more
Cytarabine: Kegunaan, Dosis, dan Efek Samping
WebJan 5, 2007 · The dose of 50 mg liposomal cytarabine was chosen based on review of prior phase 1 and 2 studies in adults (including patients aged 19 and older) and children. 9,12,13 The total number of IT treatments was chosen based on the fact that single-agent liposomal cytarabine would replace IT MTX (now eliminated) and standard cytarabine 100 mg . WebCYTARABINE - INJECTION. (sye-TAIR-uh-bean) COMMON BRAND NAME (S): Cytosar-U, Tarabine PFS. WARNING: This medication may cause serious (rarely fatal) blood disorders (bone marrow suppression leading to anemia, low number of white blood cells and platelets). Liver problems may also occur. how much is sdap
Optimal dosing of cytarabine in induction and post …
WebAug 12, 2024 · Cytarabine is a pyrimidine analog and is also known as arabinosylcytosine (ARA-C). It is converted into the triphosphate form within the cell and competes with cytidine to incorporate itself into the DNA. The sugar moiety of cytarabine hinders the rotation of the molecule within the DNA. WebCytarabine has been one of the cornerstone drugs in the treatment of acute myeloid leukemia (AML) for more than three decades.1 It was initially used in remission-induction therapy at a dose of 100... WebCytarabine Injection 2 g/20 mL is a sterile solution for intravenous, intrathecal or subcutaneous administration. Each mL contains 100 mg Cytarabine, USP, and the … how do i find my avma number